Osteogenic Growth PeptideOGP
OSTEOGENIC GROWTH PEPTIDE
CAS: 132996-61-3
Molecular Formula: C68H110N22O18
Osteogenic Growth PeptideOGP - Names and Identifiers
Osteogenic Growth PeptideOGP - Physico-chemical Properties
| Molecular Formula | C68H110N22O18 |
| Molar Mass | 1523.74 |
| Storage Condition | −20°C |
| In vitro study | Osteogenic Growth Peptide (OGP) regulates proliferation, differentiation, and matrix mineralization in osteoblast lineage cells. The active portion of OGP, the OGP(10-14) region, is cleaved from the peptide and binds to the OGP receptor which activates the MAP kinase, the Src, and the RhoA pathways. Osteogenic Growth Peptide (OGP) is a native molecule with a primary structure identical to the C-terminus of histone H4, whose sequence contains a highly conserved 14-amino acid motif (NH 2 -ALKRQGRTLYGFGG-OH). This peptide is isolated from blood during osteogenic remodeling of post-ablation of marrow regeneration. The osteogenic growth peptide (OGP) and its C-terminal pentapeptide OGP(10-14) have been shown to stimulate the proliferation, differentiation, alkaline phosphatase activity and matrix mineralization of osteoblastic lineage cells. |
Osteogenic Growth PeptideOGP - Introduction
Amino acid sequence: Ala-Leu-Lys-Arg-Gln-Gly-Arg-Thr-Leu-Tyr-Gly-Phe-Gly-Gly
Last Update：2022-10-16 17:41:12
Osteogenic Growth PeptideOGP - Reference Information
| biological activity | Osteogenic Growth Peptide, OGP is a polypeptide composed of 14 amino acid residues, a promoting factor that has a systemic response to bone marrow damage and exists in mammalian serum at a concentration of μM. |
| in vitro study | Osteogenic Growth Peptide (OGP) regulates proliferation, differentiation, and matrix mineralization in osteoblast lineage cells. The active portion of OGP, the OGP(10-14) region, is cleaved from the peptide and binds to the OGP receptor which activates the MAP kinase, the Src, and the RhoA pathways. Osteogenic Growth Peptide (OGP) is a native molecule with a primary structure identical to the C- terminus of histone H4, whose sequence contains a high conserved 14-amino acid motif (NH 2 -ALKRQGRTLYGFGG-OH). This peptide is isolated from blood during osteogenic remodeling of post-ablation of marrow regeneration. The osteogenic growth peptide (OGP) and its C- terminal pentapeptide OGP(10-14) have been shown to stimulate the proliferation, differentiation, alkaline phosphatase activity and matrix mineralization of osteoblastic lineage cells. |
Last Update：2024-04-09 20:52:54
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Featured ProductsSpot supply
Product Name: Osteogenic Growth Peptide Visit Supplier Webpage Request for quotationCAS: 132996-61-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
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Product Name: OsteogenicGrowthPeptide Request for quotationCAS: 132996-61-3
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Osteogenic Growth Peptide, OGP Visit Supplier Webpage Request for quotationCAS: 132996-61-3
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: OSTEOGENIC GROWTH PEPTIDE Visit Supplier Webpage Request for quotationCAS: 132996-61-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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